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Objective: To identify risk factors associated with failed extubation in adult patients hospitalized in an intensive care unit of a level III hospital of Cali, during the period of June 2012 to June 2014. Materials and methods: Case-control study of adult patients requiring mechanical ventilation greater than 48 hours. Patients who failed extubation (cases) were compared with patients who were successfully extubated (control), age, oxygenation index PaO2/FIO2, fluid balance, hemoglobin, days of mechanical ventilation, type of weaning and mortality were analyzed. Results: The study population consisted of 130 patients, of whom 26 (20%) had failed extubation (cases). There were no significant differences between the groups regarding age, gender, diagnosis and comorbidities. Prolonged weaning was the only factor associated with failed extubation 3,17 (95% ci 1,01-9,90). No statistically significant relationship between PaO2/FIO2, Hb, fluid balance or Apache II scale and the occurrence of failed extubation were observed. Mortality was higher in the case group (23,1% vs 2,9%) with an or 10,1 (95% ci 1,9-65,8). Conclusions: Prolonged weaning was the only factor associated with extubation failure. The risk of dying from a patient with a failed extubation was 10 times the risk of a patient with a successful extubation.

Deiby Alomía, Universidad del Valle. SOFIRE, Clínica Amiga Comfandi, Cali Colombia.

Ft. Universidad del Valle. SOFIRE, Clínica Amiga Comfandi, Cali Colombia.

Mirdza Coral, Universidad del Valle. SOFIRE, Clínica Amiga Comfandi, Cali Colombia.

Ft. Universidad del Valle. SOFIRE, Clínica Amiga Comfandi, Cali Colombia.

Sindy Ortegón, Universidad del Valle. SOFIRE, Clínica Amiga Comfandi, Cali Colombia.

Ft. Universidad del Valle. SOFIRE, Clínica Amiga Comfandi, Cali Colombia.

Rodolfo Soto, Departamento de Cirugía Centro Médico Imbanaco, Cali Colombia.

Departamento de Cirugía Centro Médico Imbanaco, Cali Colombia. 

Vilma Muñoz, Universidad del Valle. SOFIRE, Clínica Amiga Comfandi, Cali Colombia.

Universidad del Valle. SOFIRE, Clínica Amiga Comfandi, Cali Colombia.
Alomía D., Coral, M., Ortegón S., Soto, R., & Muñoz V. (2017). Risk factors Associated to Extubation Failure in Adult Patients in an Intensive Care Unit of the City of Cali. Revista Ciencias De La Salud, 15(2), 237–246. https://doi.org/10.12804/revistas.urosario.edu.co/revsalud/a.5760

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