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Research shows that subjective wellbeing (SWB) is of high relevance in the developmental period of adolescence, with many researchers emphasizing the importance of a concrete and multidimensional conceptualisation. In this study we aim to explore predictors of domain-specific aspects of SWB in a sample of students between 12 and 18 years old in Uruguay. The Personal wellbeing index (PWI) was used to assess the global level of SWB and the scores of the seven SWB domains (standard of living, health, achievements, relationships with others [peers and family], safety, community-connectedness, and future security). The Adolescents self-report, the national alcohol survey (JND) and the cannabis screening test (CAST) were used to assess psychopathology and resilience, alcohol and marijuana use, respectively. Adolescents reported highest satisfaction with the domain of community-connectedness and least satisfaction with the domain of safety. Multivariate linear regression analyses indicated the existence of domain-specific determinants for the different domains of SWB. The domain safety was most influenced by the selected variables of interest, while these variables had a rather limited impact on the domain health. Implications for prevention and clinical interventions in the context of schools, consultation to parents and teachers, and psychological assessment and treatment are discussed.

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